WOUND HEALING

WOUND HEALING

PROJECT — Egiderma: An Advanced Dressing for Complex Wounds

Poject contact person: Prof. Rossella Dorati, Dr. Erika Maria Tottoli, Dr. Enrica Chiesa

Email – rossella.dorati@unipv.it

Abstract 

Complex wounds are the major snowballing threat to public health and the economy. They are defined as a silent epidemic, impacting nearly 15% of US Medicare beneficiaries (8.2 million patients), and a conservative estimate of their annual cost is $28 billion. If we include wounds as a secondary diagnosis, the cost skyrockets up to $96.8 billion. Hypertrophic scars are common complications of complex wounds, and they can result from aberrant wound inflammation response or infection. Scars and associated functional as well as aesthetic concerns represent a huge burden on health care. Egiderma solves the problem associated with complex wounds and hypertrophic scars. Featuring a patented (WO2021064673A1, 2020) fiber technology, Egiderma guarantees optimal wound management enabling patients to achieve a complete and functional recovery even in cases when the function is impaired. Laced with ancillary agents that prevent hypertrophic scars and infections, Egiderma is the go-to treatment for complex wounds such as those arising from severe burns. The continuous fine micro -and nano-sized fibers make up Egiderma fabric to achieve a controlled release of both antifibrotic and antibiotic agents for three days preventing the onset of hypertrophic scars. The Egiderma project has been funded by Blue Sky Research Project (Young Investigator) Funds: BSR 2017 (University of Pavia), Project # BSR1741073 and by Vertis Venture, VV3TT POC Venture Program Edition 2020.

Keywords – Hyperthrophic scar, advanced dressing, electrospun fibers, medical device